There is something about the idea of a two-column page layout that I really love, leaving a space for "footnotes" (which is a concept that doesn't really make sense in an endlessly scolling page, but possibly more useful in a hyperlinked medium).

Next time I'm building a design for a website, I'm probably going to use this as a starting point. (Which is probably going to be the long-overdue rebuild of MyElectronicBrain.com - which used a few of these principles in its first iteration.)